Last Updated 9.04.08 Copyright 2008 by the President and Fellows of Harvard College.



Core Director: Ruth Ruprecht, MD, PhD
ruth_ruprecht@dfci.harvard.edu
Associate Director: Mark Cayabyab, PhD
mcayabya@caregroup.harvard.edu
Associate Director: Andrew Luster, MD, PhD
aluster@mgh.harvard.edu


The CFAR Small Animal Core, through the Animal Biocontainment Suite Facility (ABC Facility) at the DFCI, will provide CFAR investigators with the following services:

  1. The use of an animal facility, in which the spread of contagious agents is prevented between animals.
  2. Technical support in handling animals potentially infectious to humans or animals.

  3. Access to technical support for performing HIV inoculations into chimeric SCID mice, which will be used to evaluate candidate antiviral agents for efficacy and toxicity in this in vivo system. The facility also has the capability in the future to conduct HIV inoculations into transgenic mice capable of supporting HIV replication (should such animals become available as a result of new insights into the role of chemokine receptors).

  4. Use of safe working conditions.

  5. Training for safe handling of potential human pathogens in animals.


  
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